Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury

While central nervous system (CNS) microglia have been studied extensively, surprisingly little is known about macrophages populating the peripheral nervous system (PNS Macs). We performed ontogenic, transcriptomic and spatial characterization of sciatic nerve Macs (snMacs). Using multiple fate-mapp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Neurosci
Prif Awduron: Ydens, Elke, Amann, Lukas, Asselbergh, Bob, Scott, Charlotte L., Martens, Liesbet, Sichien, Dorine, Mossad, Omar, Blank, Thomas, De Prijck, Sofie, Low, Donovan, Masuda, Takahiro, Saeys, Yvan, Timmerman, Vincent, Stumm, Ralf, Ginhoux, Florent, Prinz, Marco, Janssens, Sophie, Guilliams, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611025/
https://ncbi.nlm.nih.gov/pubmed/32284604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-0618-6
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