Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury

While central nervous system (CNS) microglia have been studied extensively, surprisingly little is known about macrophages populating the peripheral nervous system (PNS Macs). We performed ontogenic, transcriptomic and spatial characterization of sciatic nerve Macs (snMacs). Using multiple fate-mapp...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Ydens, Elke, Amann, Lukas, Asselbergh, Bob, Scott, Charlotte L., Martens, Liesbet, Sichien, Dorine, Mossad, Omar, Blank, Thomas, De Prijck, Sofie, Low, Donovan, Masuda, Takahiro, Saeys, Yvan, Timmerman, Vincent, Stumm, Ralf, Ginhoux, Florent, Prinz, Marco, Janssens, Sophie, Guilliams, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611025/
https://ncbi.nlm.nih.gov/pubmed/32284604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-0618-6
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