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The Exosome Subunit Rrp44 Plays a Direct Role in RNA Substrate Recognition

The exosome plays key roles in RNA maturation and surveillance, but it is unclear how target RNAs are identified. We report the functional characterization of the yeast exosome component Rrp44, a member of the RNase II family. Recombinant Rrp44 and the purified TRAMP polyadenylation complex each spe...

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Publicat a:Mol Cell
Autors principals: Schneider, Claudia, Anderson, James T., Tollervey, David
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610968/
https://ncbi.nlm.nih.gov/pubmed/17643380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.06.006
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