Geospatial immune variability illuminates differential evolution of lung adenocarcinoma

Remarkable progress in molecular analyses has improved our understanding of the evolution of cancer cells towards immune escape(1–5). However, the spatial configurations of immune and stromal cells, which may shed light on the evolution of immune escape across tumor geographical locations, remain un...

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Pubblicato in:Nat Med
Autori principali: AbdulJabbar, Khalid, Raza, Shan E Ahmed, Rosenthal, Rachel, Jamal-Hanjani, Mariam, Veeriah, Selvaraju, Akarca, Ayse, Lund, Tom, Moore, David A., Salgado, Roberto, 6Bakir, Maise Al, Zapata, Luis, Hiley, Crispin T., Officer, Leah, Sereno, Marco, Smith, Claire Rachel, Loi, Sherene, Hackshaw, Allan, Marafioti, Teresa, Quezada, Sergio A., McGranahan, Nicholas, Quesne, John Le, Swanton, Charles, Yuan, Yinyin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610840/
https://ncbi.nlm.nih.gov/pubmed/32461698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-020-0900-x
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