A bispecific antibody strategy to target multiple type 2 cytokines in asthma

BACKGROUND: Asthma is a chronic inflammatory airway disease in which innate and adaptive immune cells act together to cause eosinophilic inflammation, goblet cell metaplasia (GCM) and bronchial hyperreactivity (BHR). In clinical trials employing biologicals against interleukin (IL)-4Rα or IL-5, only...

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Detaylı Bibliyografya
Yayımlandı:J Allergy Clin Immunol
Asıl Yazarlar: Godar, Marie, Deswarte, Kim, Vergote, Karl, Saunders, Michael, de Haard, Hans, Hammad, Hamida, Blanchetot, Christophe, Lambrecht, Bart N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610797/
https://ncbi.nlm.nih.gov/pubmed/29890236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.06.002
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