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Reconstitution of autophagosome nucleation defines Atg9 vesicles as seeds for membrane formation
Autophagosomes form de novo in a manner that is incompletely understood. Particularly enigmatic are Atg9 containing vesicles that are required for autophagy machinery assembly but do not supply the bulk of the autophagosomal membrane. Here we reconstituted autophagosome nucleation using recombinant...
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| Опубликовано в: : | Science |
|---|---|
| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610778/ https://ncbi.nlm.nih.gov/pubmed/32883836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz7714 |
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