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Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin

Characterization of the progression of cellular states during human embryogenesis can provide insights into the origin of pediatric diseases. We examined the transcriptional states of neural crest- and mesoderm-derived lineages differentiating into adrenal glands, kidneys, endothelium, and hematopoi...

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Foilsithe in:Nat Genet
Main Authors: Kameneva, Polina, Artemov, Artem V., Kastriti, Maria Eleni, Faure, Louis, Olsen, Thale K., Otte, Jörg, Erickson, Alek, Semsch, Bettina, Andersson, Emma R., Ratz, Michael, Frisen, Jonas, Tischler, Arthur S., de Krijger, Ronald R., Bouderlique, Thibault, Akkuratova, Natalia, Vorontsova, Maria, Gusev, Oleg, Fried, Kaj, Sundstrom, Erik, Mei, Shenglin, Kogner, Per, Baryawno, Ninib, Kharchenko, Peter V., Adameyko, Igor
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610777/
https://ncbi.nlm.nih.gov/pubmed/33833454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-021-00818-x
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