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dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments

Recent single-cell RNA-seq protocols based on droplet microfluidics use massively multiplexed barcoding to enable simultaneous measurements of transcriptomes for thousands of individual cells. The increasing complexity of such data creates challenges for subsequent computational processing and troub...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Petukhov, Viktor, Guo, Jimin, Baryawno, Ninib, Severe, Nicolas, Scadden, David T., Samsonova, Maria G., Kharchenko, Peter V.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010209/
https://ncbi.nlm.nih.gov/pubmed/29921301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1449-6
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