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CARMN Loss Regulates Smooth Muscle Cells and Accelerates Atherosclerosis in Mice

RATIONALE: In the microenvironment of atherosclerotic lesions, vascular smooth muscle cells (vSMCs) switch to a dedifferentiated state but the underlying molecular mechanisms driving this switch are not fully understood. Long noncoding RNAs (lncRNAs) are dysregulated during vascular pathology, but r...

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Vydáno v:Circ Res
Hlavní autoři: Vacante, Francesca, Rodor, Julie, Lalwani, Mukesh K., Mahmoud, Amira D., Bennett, Matthew, De Pace, Azzura L., Miller, Eileen, Van Kuijk, Kim, de Bruijn, Jenny, Gijbels, Marion, Williams, Thomas C., Clark, Michael B., Scanlon, Jessica P., Doran, Amanda C., Montgomery, Rusty, Newby, David E., Giacca, Mauro, O’Carroll, Dónal, Hadoke, Patrick W.F., Denby, Laura, Sluimer, Judith C., Baker, Andrew H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610708/
https://ncbi.nlm.nih.gov/pubmed/33622045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.318688
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