CARMN Loss Regulates Smooth Muscle Cells and Accelerates Atherosclerosis in Mice

RATIONALE: In the microenvironment of atherosclerotic lesions, vascular smooth muscle cells (vSMCs) switch to a dedifferentiated state but the underlying molecular mechanisms driving this switch are not fully understood. Long noncoding RNAs (lncRNAs) are dysregulated during vascular pathology, but r...

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Publicado en:Circ Res
Main Authors: Vacante, Francesca, Rodor, Julie, Lalwani, Mukesh K., Mahmoud, Amira D., Bennett, Matthew, De Pace, Azzura L., Miller, Eileen, Van Kuijk, Kim, de Bruijn, Jenny, Gijbels, Marion, Williams, Thomas C., Clark, Michael B., Scanlon, Jessica P., Doran, Amanda C., Montgomery, Rusty, Newby, David E., Giacca, Mauro, O’Carroll, Dónal, Hadoke, Patrick W.F., Denby, Laura, Sluimer, Judith C., Baker, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610708/
https://ncbi.nlm.nih.gov/pubmed/33622045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.318688
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