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Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states
RNA polymerase III (Pol III) synthesises tRNAs and other short, essential RNAs. Human Pol III misregulation is linked to tumour transformation, neurodegenerative and developmental disorders, and increased sensitivity to viral infections. Here, we present cryo-EM structures at 2.8 to 3.3 Å resolution...
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| Pubblicato in: | Nat Struct Mol Biol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610652/ https://ncbi.nlm.nih.gov/pubmed/33558764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00555-5 |
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