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Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states
RNA polymerase III (Pol III) synthesises tRNAs and other short, essential RNAs. Human Pol III misregulation is linked to tumour transformation, neurodegenerative and developmental disorders, and increased sensitivity to viral infections. Here, we present cryo-EM structures at 2.8 to 3.3 Å resolution...
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| 發表在: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610652/ https://ncbi.nlm.nih.gov/pubmed/33558764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00555-5 |
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