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Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states
RNA polymerase III (Pol III) synthesises tRNAs and other short, essential RNAs. Human Pol III misregulation is linked to tumour transformation, neurodegenerative and developmental disorders, and increased sensitivity to viral infections. Here, we present cryo-EM structures at 2.8 to 3.3 Å resolution...
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| 出版年: | Nat Struct Mol Biol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610652/ https://ncbi.nlm.nih.gov/pubmed/33558764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00555-5 |
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