Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states

RNA polymerase III (Pol III) synthesises tRNAs and other short, essential RNAs. Human Pol III misregulation is linked to tumour transformation, neurodegenerative and developmental disorders, and increased sensitivity to viral infections. Here, we present cryo-EM structures at 2.8 to 3.3 Å resolution...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Struct Mol Biol
Main Authors: Girbig, Mathias, Misiaszek, Agata D., Vorländer, Matthias K., Lafita, Aleix, Grötsch, Helga, Baudin, Florence, Bateman, Alex, Müller, Christoph W.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610652/
https://ncbi.nlm.nih.gov/pubmed/33558764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00555-5
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker