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Site-specific covalent labeling of His-tag fused proteins with N-acyl-N-alkyl sulfonamide reagent

The ability to incorporate a desired functionality into proteins of interest in a site-specific manner can provide powerful tools for investigating biological systems and creating therapeutic conjugates. However, there are not any universal methods that can be applied to all proteins, and it is thus...

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Bibliografski detalji
Izdano u:Bioorg Med Chem
Glavni autori: Thimaradka, Vikram, Oh, Jae Hoon, Heroven, Christina, Aricescu, A. Radu, Yuzaki, Michisuke, Tamura, Tomonori, Hamachi, Itaru
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610637/
https://ncbi.nlm.nih.gov/pubmed/33360195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115947
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