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A Computational Model for the AMPA Receptor Phosphorylation Master Switch Regulating Cerebellar Long-Term Depression

The expression of long-term depression (LTD) in cerebellar Purkinje cells results from the internalisation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors (AMPARs) from the postsynaptic membrane. This process is regulated by a complex signalling pathway involving sustained protein...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Gallimore, Andrew R., Aricescu, A. Radu, Yuzaki, Michisuke, Calinescu, Radu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726815/
https://ncbi.nlm.nih.gov/pubmed/26807999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004664
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