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Enhanced AMPA receptor function promotes cerebellar long-term depression rather than potentiation
Ampakines are allosteric modulators of AMPA receptors that facilitate hippocampal long-term potentiation (LTP) and learning, and have been considered for the treatment of cognition and memory deficits. Here, we show that the ampakine CX546 raises the amplitude and slows the decay time of excitatory...
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Publicado no: | Learn Mem |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4236409/ https://ncbi.nlm.nih.gov/pubmed/25403454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.035220.114 |
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