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Molecular Mechanism of Taurocholate Transport by the Bile Salt Export Pump, an ABC Transporter Associated with Intrahepatic CholestasisS
The bile salt export pump (BSEP/ABCB11) transports bile salts nucleotide binding site 1) by glutamate imparted hydrolysis from hepatocytes into bile canaliculi. Its malfunction is associ-competency to this site. Importantly, this mutation was able to ated with severe liver disease. One reason for fu...
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| 出版年: | Mol Pharmacol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610612/ https://ncbi.nlm.nih.gov/pubmed/28784620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.108688 |
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