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Folding correction of ABC‐transporter ABCB1 by pharmacological chaperones: a mechanistic concept
Point mutations of ATP‐binding cassette (ABC) proteins are a common cause of human diseases. Available crystal structures indicate a similarity in the architecture of several members of this protein family. Their molecular architecture makes these proteins vulnerable to mutation, when critical struc...
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| Vydáno v: | Pharmacol Res Perspect |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5464349/ https://ncbi.nlm.nih.gov/pubmed/28603639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.325 |
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