SARS-CoV-2 evolution during treatment of chronic infection

SARS-CoV-2 Spike protein is critical for virus infection via engagement of ACE2(1), and is a major antibody target. Here we report chronic SARS-CoV-2 with reduced sensitivity to neutralising antibodies in an immune suppressed individual treated with convalescent plasma, generating whole genome ultra...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Kemp, Steven A, Collier, Dami A, Datir, Rawlings P, Ferreira, Isabella ATM, Gayed, Salma, Jahun, Aminu, Hosmillo, Myra, Rees-Spear, Chloe, Mlcochova, Petra, Lumb, Ines Ushiro, Roberts, David J, Chandra, Anita, Temperton, Nigel, Sharrocks, Katherine, Blane, Elizabeth, Modis, Yorgo, Leigh, Kendra, Briggs, John, van Gils, Marit, Smith, Kenneth GC, Bradley, John R, Smith, Chris, Doffinger, Rainer, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Pollock, David D, Goldstein, Richard A, Smielewska, Anna, Skittrall, Jordan P, Gouliouris, Theodore, Goodfellow, Ian G, Gkrania-Klotsas, Effrossyni, Illingworth, Christopher JR, McCoy, Laura E, Gupta, Ravindra K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610568/
https://ncbi.nlm.nih.gov/pubmed/33545711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03291-y
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