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Single-molecule visualisation of DNA G-quadruplex formation in live cells

Substantial evidence now exists to support that formation of DNA G-quadruplexes (G4s) can alter gene-expression. However, approaches that allow to probe G4s in living cells without perturbing their folding dynamics are required to understand their biological roles in greater detail. Herein, we repor...

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Détails bibliographiques
Publié dans:Nat Chem
Auteurs principaux: Di Antonio, Marco, Ponjavic, Aleks, Radzevičius, Antanas, Ranasinghe, Rohan T., Catalano, Marco, Zhang, Xiaoyun, Shen, Jiazhen, Needham, Lisa-Maria, Lee, Steven F., Klenerman, David, Balasubramanian, Shankar
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610488/
https://ncbi.nlm.nih.gov/pubmed/32690897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-020-0506-4
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