Follicular helper T cell profiles predict response to costimulation blockade in type 1 diabetes

Follicular helper T cells (Tfh) are implicated in type 1 diabetes (T1D) and their development has been linked to CD28 costimulation. We tested whether Tfh were decreased by costimulation blockade using the CTLA-4-Ig fusion protein (Abatacept) in a mouse model of diabetes and in individuals with new...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Immunol
Main Authors: Edner, Natalie M., Heuts, Frank, Thomas, Niclas, Wang, Chun Jing, Petersone, Lina, Kenefeck, Rupert, Kogimtzis, Alexandros, Ovcinnikovs, Vitalijs, Ross, Ellen M., Ntavli, Elisavet, Elfaki, Yassin, Eichmann, Martin, Baptista, Roman, Ambery, Philip, Jermutus, Lutz, Peakman, Mark, Rosenthal, Miranda, Walker, Lucy S.K.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610476/
https://ncbi.nlm.nih.gov/pubmed/32747817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0744-z
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker