Načítá se...

Follicular helper T cell profiles predict response to costimulation blockade in type 1 diabetes

Follicular helper T cells (Tfh) are implicated in type 1 diabetes (T1D) and their development has been linked to CD28 costimulation. We tested whether Tfh were decreased by costimulation blockade using the CTLA-4-Ig fusion protein (Abatacept) in a mouse model of diabetes and in individuals with new...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Immunol
Hlavní autoři: Edner, Natalie M., Heuts, Frank, Thomas, Niclas, Wang, Chun Jing, Petersone, Lina, Kenefeck, Rupert, Kogimtzis, Alexandros, Ovcinnikovs, Vitalijs, Ross, Ellen M., Ntavli, Elisavet, Elfaki, Yassin, Eichmann, Martin, Baptista, Roman, Ambery, Philip, Jermutus, Lutz, Peakman, Mark, Rosenthal, Miranda, Walker, Lucy S.K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610476/
https://ncbi.nlm.nih.gov/pubmed/32747817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0744-z
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!