Follicular helper T cell signature in type 1 diabetes

The strong genetic association between particular HLA alleles and type 1 diabetes (T1D) indicates a key role for CD4(+) T cells in disease; however, the differentiation state of the responsible T cells is unclear. T cell differentiation originally was considered a dichotomy between Th1 and Th2 cells...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kenefeck, Rupert, Wang, Chun Jing, Kapadi, Tauseef, Wardzinski, Lukasz, Attridge, Kesley, Clough, Louise E., Heuts, Frank, Kogimtzis, Alexandros, Patel, Sapna, Rosenthal, Miranda, Ono, Masahiro, Sansom, David M., Narendran, Parth, Walker, Lucy S.K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382272/
https://ncbi.nlm.nih.gov/pubmed/25485678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76238
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