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Strategies for conjugating iridium(III) anticancer complexes to targeting peptides via copper-free click chemistry
We report the synthesis and characterization of novel pentamethylcyclopentadienyl (Cp*) iridium(III) complexes [(Cp*)Ir(4-methyl-4′-carboxy-2,2′-bipyridine)Cl]PF6 (Ir-I), the product (Ir-II) from amide coupling of Ir-I to dibenzocyclooctyne-amine, and its conjugate (Ir-CP) with the cyclic nona-pepti...
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| Pubblicato in: | Inorganica Chim Acta |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610455/ https://ncbi.nlm.nih.gov/pubmed/33776131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ica.2019.119396 |
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