Nucleus‐Targeted Organoiridium–Albumin Conjugate for Photodynamic Cancer Therapy

An organoiridium–albumin bioconjugate (Ir1‐HSA) was synthesized by reaction of a pendant maleimide ligand with human serum albumin. The phosphorescence of Ir1‐HSA was enhanced significantly compared to parent complex Ir1. The long phosphorescence lifetime and high (1)O(2) quantum yield of Ir1‐HSA ar...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Angew Chem Int Ed Engl
Main Authors: Zhang, Pingyu, Huang, Huaiyi, Banerjee, Samya, Clarkson, Guy J., Ge, Chen, Imberti, Cinzia, Sadler, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468315/
https://ncbi.nlm.nih.gov/pubmed/30552796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201813002
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