Organoiridium Photosensitizers Induce Specific Oxidative Attack on Proteins within Cancer Cells

Strongly luminescent iridium(III) complexes, [Ir(C,N)(2)(S,S)](+) (1) and [Ir(C,N)(2)(O,O)] (2), containing C,N (phenylquinoline), O,O (diketonate), or S,S (dithione) chelating ligands, have been characterized by X‐ray crystallography and DFT calculations. Their long phosphorescence lifetimes in liv...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Zhang, Pingyu, Chiu, Cookson K. C., Huang, Huaiyi, Lam, Yuko P. Y., Habtemariam, Abraha, Malcomson, Thomas, Paterson, Martin J., Clarkson, Guy J., O'Connor, Peter B., Chao, Hui, Sadler, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698709/
https://ncbi.nlm.nih.gov/pubmed/29047228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201709082
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