Ligand-centred redox activation of inert organoiridium anticancer catalysts

Organometallic complexes with novel activation mechanisms are attractive anticancer drug candidates. Here, we show that half-sandwich iodido cyclopentadienyl iridium(iii) azopyridine complexes exhibit potent antiproliferative activity towards cancer cells, in most cases more potent than cisplatin. D...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Chem Sci
Päätekijät: Zhang, Wen-Ying, Banerjee, Samya, Hughes, George M., Bridgewater, Hannah E., Song, Ji-Inn, Breeze, Ben G., Clarkson, Guy J., Coverdale, James P. C., Sanchez-Cano, Carlos, Ponte, Fortuna, Sicilia, Emilia, Sadler, Peter J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Royal Society of Chemistry 2020
Aiheet:
Chemistry
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159363/
https://ncbi.nlm.nih.gov/pubmed/34094073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc00897d
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