Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination

Proregenerative responses are required for the restoration of nervous-system functionality in demyelinating diseases such as multiple sclerosis (MS). Yet, the limiting factors responsible for poor CNS repair are only partially understood. Here, we test the impact of a Western diet (WD) on phagocyte...

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Publicat a:Nat Metab
Autors principals: Bosch-Queralt, Mar, Cantuti-Castelvetri, Ludovico, Damkou, Alkmini, Schifferer, Martina, Schlepckow, Kai, Alexopoulos, Ioannis, Lütjohann, Dieter, Klose, Christian, Vaculčiaková, Lenka, Masuda, Takahiro, Prinz, Marco, Monroe, Kathryn M., Di Paolo, Gilbert, Lewcock, Joseph W., Haass, Christian, Simons, Mikael
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610359/
https://ncbi.nlm.nih.gov/pubmed/33619376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-021-00341-7
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