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Elite suppressors have low frequencies of intact HIV-1 proviral DNA

Elite controllers or suppressors (ES) control viral replication without antiretroviral therapy (ART). We used the intact proviral DNA assay to approximate the size of the inducible latent reservoir in ES and found that while the median frequency of both total and intact proviral DNA was markedly low...

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Pubblicato in:AIDS
Autori principali: KWAA, Abena KR, GARLISS, Caroline C., RITTER, Kristen D., LAIRD, Gregory M., BLANKSON, Joel N
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610219/
https://ncbi.nlm.nih.gov/pubmed/31895150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002474
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