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Power loss due to testing association between covariate adjusted traits and genetic variants

Multiple linear regression is commonly used to test for association between genetic variants and continuous traits and estimate genetic effect sizes. Confounding variables are controlled for by including them as additional covariates. An alternative technique that is increasingly used is to regress...

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Bibliographische Detailangaben
Veröffentlicht in:Genet Epidemiol
Hauptverfasser: Yajnik, Pranav, Boehnke, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610149/
https://ncbi.nlm.nih.gov/pubmed/32511788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22325
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