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Powerful Genetic Association Analysis for Common or Rare Variants with High-Dimensional Structured Traits

Many genetic association studies collect a wide range of complex traits. As these traits may be correlated and share a common genetic mechanism, joint analysis can be statistically more powerful and biologically more meaningful. However, most existing tests for multiple traits cannot be used for hig...

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Détails bibliographiques
Publié dans:Genetics
Auteurs principaux: Zhan, Xiang, Zhao, Ni, Plantinga, Anna, Thornton, Timothy A., Conneely, Karen N., Epstein, Michael P., Wu, Michael C.
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560787/
https://ncbi.nlm.nih.gov/pubmed/28642271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.199646
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