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A Powerful Pathway-Based Adaptive Test for Genetic Association with Common or Rare Variants
In spite of the success of genome-wide association studies (GWASs), only a small proportion of heritability for each complex trait has been explained by identified genetic variants, mainly SNPs. Likely reasons include genetic heterogeneity (i.e., multiple causal genetic variants) and small effect si...
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| Publicado no: | Am J Hum Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572508/ https://ncbi.nlm.nih.gov/pubmed/26119817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.05.018 |
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