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A Data-Adaptive Sum Test for Disease Association with Multiple Common or Rare Variants

Since associations between complex diseases and common variants are typically weak, and approaches to genotyping rare variants (e.g. by next-generation resequencing) multiply, there is an urgent demand to develop powerful association tests that are able to detect disease associations with both commo...

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Detalhes bibliográficos
Main Authors: Han, Fang, Pan, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912645/
https://ncbi.nlm.nih.gov/pubmed/20413981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000288704
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