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A Data-Adaptive Sum Test for Disease Association with Multiple Common or Rare Variants

Since associations between complex diseases and common variants are typically weak, and approaches to genotyping rare variants (e.g. by next-generation resequencing) multiply, there is an urgent demand to develop powerful association tests that are able to detect disease associations with both commo...

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Autori principali: Han, Fang, Pan, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912645/
https://ncbi.nlm.nih.gov/pubmed/20413981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000288704
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