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A Powerful Pathway-Based Adaptive Test for Genetic Association with Common or Rare Variants
In spite of the success of genome-wide association studies (GWASs), only a small proportion of heritability for each complex trait has been explained by identified genetic variants, mainly SNPs. Likely reasons include genetic heterogeneity (i.e., multiple causal genetic variants) and small effect si...
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| Publié dans: | Am J Hum Genet |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572508/ https://ncbi.nlm.nih.gov/pubmed/26119817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.05.018 |
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