The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies

Dementia with Lewy bodies (DLB) represents a huge medical need as it accounts for up to 30% of all dementia cases, and there is no cure available. The underyling spectrum of pathology is complex and creates a challenge for targeted molecular therapies. We here tested the hypothesis that leukotrienes...

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Vydáno v:Neurotherapeutics
Hlavní autoři: Marschallinger, Julia, Altendorfer, Barbara, Rockenstein, Edward, Holztrattner, Miriam, Garnweidner-Raith, Julia, Pillichshammer, Nadine, Leister, Iris, Hutter-Paier, Birgit, Strempfl, Katharina, Unger, Michael S., Chishty, Mansoor, Felder, Thomas, Johnson, Mary, Attems, Johannes, Masliah, Eliezer, Aigner, Ludwig
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609773/
https://ncbi.nlm.nih.gov/pubmed/32072462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-020-00836-3
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