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Improved Bioavailability of Montelukast through a Novel Oral Mucoadhesive Film in Humans and Mice

The leukotriene receptor antagonist Montelukast (MTK) is an approved medication for the treatment of asthma and allergic rhinitis. The existing marketed tablet forms of MTK exhibit inconsistent uptake and bioavailability, which partially explains the presence of a significant proportion of MTK low-...

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Publicat a:Pharmaceutics
Autors principals: Michael, Johanna, Bessa de Sousa, Diana, Conway, Justin, Gonzalez-Labrada, Erick, Obeid, Rodolphe, Tevini, Julia, Felder, Thomas, Hutter-Paier, Birgit, Zerbe, Horst, Paiement, Nadine, Aigner, Ludwig
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822410/
https://ncbi.nlm.nih.gov/pubmed/33374646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13010012
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