Wake-Promoting and EEG Spectral Effects of Modafinil After Acute or Chronic Administration in the R6/2 Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is characterised by progressive symptoms including cognitive deficits and sleep/wake disturbances reflected in an abnormal electroencephalography (EEG). Modafinil, a wake-promoting and cognitive-enhancing drug, has been considered as a treatment for HD. We used HD (R6/2) mi...

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Publicado en:Neurotherapeutics
Autores principales: Vas, Szilvia, Casey, Jackie M., Schneider, Will T., Kalmar, Lajos, Morton, A. Jennifer
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609772/
https://ncbi.nlm.nih.gov/pubmed/32297185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-020-00849-y
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