Beneficial effects of environmental enrichment and food entrainment in the R6/2 mouse model of Huntington's disease

BACKGROUND: In addition to their cognitive and motor deficits, R6/2 mice show a progressive disintegration in circadian rhythms that mirrors the problems associated with sleep-wake disturbances experienced by patients with Huntington's disease (HD). It has been shown previously that motor and c...

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Main Authors: Skillings, Elizabeth A, Wood, Nigel I, Morton, A Jennifer
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Publishing Ltd 2014
נושאים:
Original Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107380/
https://ncbi.nlm.nih.gov/pubmed/25328844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.235
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