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Abnormally abrupt transitions from sleep-to-wake in Huntington’s disease sheep (Ovis aries) are revealed by automated analysis of sleep/wake transition dynamics

Sleep disturbance is a common and disruptive symptom of neurodegenerative diseases such as Alzheimer’s and Huntington’s disease (HD). In HD patients, sleep fragmentation appears at an early stage of disease, although features of the earliest sleep abnormalities in presymptomatic HD are not fully est...

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Udgivet i:PLoS One
Main Authors: Schneider, William T., Vas, Szilvia, Nicol, Alister U., Morton, A. Jennifer
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8118338/
https://ncbi.nlm.nih.gov/pubmed/33984047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251767
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