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Glucocorticoid-dependent transcription in skin requires epidermal expression of the glucocorticoid receptor and is modulated by the mineralocorticoid receptor

Glucocorticoid (GC) actions are mediated through two closely related ligand-dependent transcription factors, the GC receptor (GR) and the mineralocorticoid receptor (MR). Given the wide and effective use of GCs to combat skin inflammatory diseases, it is important to understand the relative contribu...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Sevilla, Lisa M., Bigas, Judit, Chiner-Oms, Álvaro, Comas, Iñaki, Sentandreu, Vicente, Pérez, Paloma
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609727/
https://ncbi.nlm.nih.gov/pubmed/33144612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75853-5
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