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Glucocorticoid-dependent transcription in skin requires epidermal expression of the glucocorticoid receptor and is modulated by the mineralocorticoid receptor

Glucocorticoid (GC) actions are mediated through two closely related ligand-dependent transcription factors, the GC receptor (GR) and the mineralocorticoid receptor (MR). Given the wide and effective use of GCs to combat skin inflammatory diseases, it is important to understand the relative contribu...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Sevilla, Lisa M., Bigas, Judit, Chiner-Oms, Álvaro, Comas, Iñaki, Sentandreu, Vicente, Pérez, Paloma
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609727/
https://ncbi.nlm.nih.gov/pubmed/33144612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-75853-5
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