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Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity

Every year, species of the Mycobacterium tuberculosis complex (MTBC) kill more people than any other infectious disease caused by a single agent. As a consequence of its global distribution and parallel evolution with the human host the bacteria is not genetically homogeneous. The observed genetic h...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chiner-Oms, Álvaro, González-Candelas, Fernando, Comas, Iñaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830583/
https://ncbi.nlm.nih.gov/pubmed/29491462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22237-5
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