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Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity

Every year, species of the Mycobacterium tuberculosis complex (MTBC) kill more people than any other infectious disease caused by a single agent. As a consequence of its global distribution and parallel evolution with the human host the bacteria is not genetically homogeneous. The observed genetic h...

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Vydáno v:Sci Rep
Hlavní autoři: Chiner-Oms, Álvaro, González-Candelas, Fernando, Comas, Iñaki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830583/
https://ncbi.nlm.nih.gov/pubmed/29491462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22237-5
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