Simvastatin ameliorates altered mechanotransduction in uterine leiomyoma cells

BACKGROUND: Uterine leiomyomas, the most common tumors of the female reproductive system, feature excessive deposition of disordered stiff extracellular matrix (ECM) and fundamentally altered mechanical signaling pathways. Specifically, these alterations impact the normal dynamic state of responsive...

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Vydáno v:Am J Obstet Gynecol
Hlavní autoři: AFRIN, Sadia, ISLAM, Md Soriful, PATZKOWSKY, Kristin, MALIK, Minnie, CATHERINO, William H., SEGARS, James H., BORAHAY, Mostafa A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609626/
https://ncbi.nlm.nih.gov/pubmed/32417359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2020.05.012
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