Extracellular matrix and Hippo signaling as therapeutic targets of antifibrotic compounds for uterine fibroids
Abstract Background Uterine fibroids are highly prevalent, collagen‐rich, mechanically stiff, fibrotic tumors for which new therapeutic options are needed. Increased extracellular matrix (ECM) stiffness activates mechanical signaling and Hippo/YAP promoting fibroid growth, but no prior studies have...
Gardado en:
| Principais autores: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Wiley
2021-07-01
|
| Series: | Clinical and Translational Medicine |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1002/ctm2.475 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|