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Disorders caused by genetic defects associated with GH-dependent genes: PAPPA2 defects.
Growth hormone (GH) and its mediator, insulin-like growth factor-1 (IGF-1), have long been recognized as central to human growth physiology. IGF-1 is known to complex with IGF binding proteins as well as with the acid labile subunit (ALS) in order to prolong its half-life in circulation. Factors reg...
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| Udgivet i: | Mol Cell Endocrinol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7609568/ https://ncbi.nlm.nih.gov/pubmed/32739295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2020.110967 |
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