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Human Growth Disorders Associated with Impaired GH action: Defects in STAT5B and JAK2
Growth hormone (GH) promotes postnatal human growth primarily by regulating insulin-like growth factor (IGF)-I production through activation of the GH receptor (GHR)-JAK2-signal transducer and activator of transcription (STAT)-5B signaling pathway. Inactivating STAT5B mutations, both autosomal reces...
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| Publicado no: | Mol Cell Endocrinol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736371/ https://ncbi.nlm.nih.gov/pubmed/33122102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2020.111063 |
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