Impact of APOE-ε4 carriage on the onset and rates of neocortical Aβ-amyloid deposition

Neocortical Aβ-amyloid deposition, one of the hallmark pathologic features of Alzheimer’s disease (AD), begins decades prior to the presence of clinical symptoms. As clinical trials move to secondary and even primary prevention, understanding the rates of neocortical Aβ-amyloid deposition and the ag...

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Gepubliceerd in:Neurobiol Aging
Hoofdauteurs: Burnham, Samantha C., Laws, Simon M., Budgeon, Charley A., Doré, Vincent, Porter, Tenielle, Bourgeat, Pierrick, Buckley, Rachel F., Murray, Kevin, Ellis, Kathryn A., Turlach, Berwin A., Salvado, Olivier, Ames, David, Martins, Ralph N, Rentz, Dorene, Masters, Colin L., Rowe, Christopher C., Villemagne, Victor L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609543/
https://ncbi.nlm.nih.gov/pubmed/32750666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.06.001
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