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Unveiling Druggable Pockets by Site-Specific Protein Modification: Beyond Antibody-Drug Conjugates

Site-specific modification approaches have been extensively employed in the development of protein-based technologies. In this field, stability and activity integrity are the envisioned features of chemically modified proteins. These methods are especially used in the design of antibody-drug conjuga...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Martínez, Dailén G., Hüttelmaier, Stefan, Bertoldo, Jean B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609475/
https://ncbi.nlm.nih.gov/pubmed/33195086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.586942
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