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Methods for site-specific drug conjugation to antibodies

Antibody drug conjugates (ADCs) are an emerging class of targeted therapeutics with the potential to improve therapeutic index over traditional chemotherapy. Drugs and linkers have been the current focus of ADC development, in addition to antibody and target selection. Recently, however, the importa...

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Bibliografske podrobnosti
Main Authors: Behrens, Christopher R, Liu, Bin
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929454/
https://ncbi.nlm.nih.gov/pubmed/24135651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.26632
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