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Methods for site-specific drug conjugation to antibodies

Antibody drug conjugates (ADCs) are an emerging class of targeted therapeutics with the potential to improve therapeutic index over traditional chemotherapy. Drugs and linkers have been the current focus of ADC development, in addition to antibody and target selection. Recently, however, the importa...

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Detalles Bibliográficos
Autores principales: Behrens, Christopher R, Liu, Bin
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929454/
https://ncbi.nlm.nih.gov/pubmed/24135651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.26632
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