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Enzyme kinetics and inhibition parameters of human leukocyte glucosylceramidase
Glucosylceramidase (GCase) is a lysosomal enzyme that catalyzes the cleavage of β-glucosidic linkage of glucocerebroside (GC) into glucose and ceramide; thereby, plays an essential function in the degradation of complex lipids and the turnover of cellular membranes. The growing list of 460 mutations...
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| Publié dans: | Heliyon |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7609449/ https://ncbi.nlm.nih.gov/pubmed/33163670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e05191 |
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